Development of a Dictyostelium discoideum (slime mould) based rapid drug screening system to identify potential anti-protozoan drugs

Authors Organisations
Type

Student thesis: Master's ThesisMaster of Philosophy

Original languageEnglish
Awarding Institution
Supervisors/Advisors
Award date2022
Links
View graph of relations

Abstract

Dictyostelium discoideum is a free living social amoeba, which are able to change from a single celled organism to multicellular organism when in starvation condition. In this study, D. dicsoideum is being utilised as a model organism to screen over 400 compounds for activity against pathogenic protozoans. The technique evaluated using an agar based assay. Furthermore, three compounds were also identified as promising for further investigation for their anti-protozoan activity properties

Documents

  • Collett_Shane

    Thesis, 5.42 MB, PDF

    Embargo end date: 31 Dec 2024

Documents

  • Collett_Shane

    Thesis, 5.42 MB, PDF

    Embargo end date: 31 Dec 2024

    Request copy