Effects of bovine colostrum supplementation on upper respiratory illness in active males

Arwel W. Jones; Simon J. S. Cameron; Rhys Thatcher; Marikka Shannon Beecroft; Luis A. J. Mur; Glen Davison

doi:10.1016/j.bbi.2013.10.032

Effects of bovine colostrum supplementation on upper respiratory illness in active males

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Effects of bovine colostrum supplementation on upper respiratory illness in active males. / Jones, Arwel W.; Cameron, Simon J. S.; Thatcher, Rhys et al.

In: Brain, Behavior, and Immunity, Vol. 39, 07.2014, p. 194-203.

Research output: Contribution to journal › Article › peer-review

Harvard

Jones, AW, Cameron, SJS, Thatcher, R, Beecroft, MS, Mur, LAJ & Davison, G 2014, 'Effects of bovine colostrum supplementation on upper respiratory illness in active males', Brain, Behavior, and Immunity, vol. 39, pp. 194-203. https://doi.org/10.1016/j.bbi.2013.10.032

APA

Jones, A. W., Cameron, S. J. S., Thatcher, R., Beecroft, M. S., Mur, L. A. J., & Davison, G. (2014). Effects of bovine colostrum supplementation on upper respiratory illness in active males. Brain, Behavior, and Immunity, 39, 194-203. https://doi.org/10.1016/j.bbi.2013.10.032

Vancouver

Jones AW, Cameron SJS, Thatcher R, Beecroft MS, Mur LAJ, Davison G. Effects of bovine colostrum supplementation on upper respiratory illness in active males. Brain, Behavior, and Immunity. 2014 Jul;39:194-203. Epub 2013 Nov 4. doi: 10.1016/j.bbi.2013.10.032

Author

Jones, Arwel W. ; Cameron, Simon J. S. ; Thatcher, Rhys et al. / Effects of bovine colostrum supplementation on upper respiratory illness in active males. In: Brain, Behavior, and Immunity. 2014 ; Vol. 39. pp. 194-203.

Bibtex - Download

@article{658209c84db74ec6aa91ed517f950145,

title = "Effects of bovine colostrum supplementation on upper respiratory illness in active males",

abstract = "Bovine colostrum (COL) has been advocated as a nutritional countermeasure to exercise-induced immune dysfunction and increased risk of upper respiratory illness (URI) in athletic populations, however, the mechanisms remain unclear. During winter months, under double-blind procedures, 53 males (mean training load±SD, 50.5±28.9 MET-hweek(-1)) were randomized to daily supplementation of 20g of COL (N=25) or an isoenergetic/isomacronutrient placebo (PLA) (N=28) for 12weeks. Venous blood was collected at baseline and at 12weeks and unstimulated saliva samples at 4 weeks intervals. There was a significantly lower proportion of URI days and number of URI episodes with COL compared to PLA over the 12weeks (p0.05), which does not support previously suggested mechanisms. In a subset of participants (COL=14, PLA=17), real-time quantitative PCR, targeting the 16S rRNA gene showed there was an increase in salivary bacterial load over the 12 weeks period with PLA (p",

keywords = "URTI, innate immunity, mucosal immunity, microbiome, 16S rRNA, metabolomics",

author = "Jones, {Arwel W.} and Cameron, {Simon J. S.} and Rhys Thatcher and Beecroft, {Marikka Shannon} and Mur, {Luis A. J.} and Glen Davison",

note = "Jones, A. W., Cameron, S. J. S., Thatcher, R., Beecroft, M. S., Mur, L. A. J., Davison, G. (2014). Effects of bovine colostrum supplementation on upper respiratory illness in active males. Brain, Behavior, and Immunity, 39, 194-203 Copyright {\textcopyright} 2013 Elsevier Inc. All rights reserved.",

year = "2014",

month = jul,

doi = "10.1016/j.bbi.2013.10.032",

language = "English",

volume = "39",

pages = "194--203",

journal = "Brain, Behavior, and Immunity",

issn = "0889-1591",

publisher = "Elsevier",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Effects of bovine colostrum supplementation on upper respiratory illness in active males

AU - Jones, Arwel W.

AU - Cameron, Simon J. S.

AU - Thatcher, Rhys

AU - Beecroft, Marikka Shannon

AU - Mur, Luis A. J.

AU - Davison, Glen

N1 - Jones, A. W., Cameron, S. J. S., Thatcher, R., Beecroft, M. S., Mur, L. A. J., Davison, G. (2014). Effects of bovine colostrum supplementation on upper respiratory illness in active males. Brain, Behavior, and Immunity, 39, 194-203 Copyright © 2013 Elsevier Inc. All rights reserved.

PY - 2014/7

Y1 - 2014/7

N2 - Bovine colostrum (COL) has been advocated as a nutritional countermeasure to exercise-induced immune dysfunction and increased risk of upper respiratory illness (URI) in athletic populations, however, the mechanisms remain unclear. During winter months, under double-blind procedures, 53 males (mean training load±SD, 50.5±28.9 MET-hweek(-1)) were randomized to daily supplementation of 20g of COL (N=25) or an isoenergetic/isomacronutrient placebo (PLA) (N=28) for 12weeks. Venous blood was collected at baseline and at 12weeks and unstimulated saliva samples at 4 weeks intervals. There was a significantly lower proportion of URI days and number of URI episodes with COL compared to PLA over the 12weeks (p0.05), which does not support previously suggested mechanisms. In a subset of participants (COL=14, PLA=17), real-time quantitative PCR, targeting the 16S rRNA gene showed there was an increase in salivary bacterial load over the 12 weeks period with PLA (p

AB - Bovine colostrum (COL) has been advocated as a nutritional countermeasure to exercise-induced immune dysfunction and increased risk of upper respiratory illness (URI) in athletic populations, however, the mechanisms remain unclear. During winter months, under double-blind procedures, 53 males (mean training load±SD, 50.5±28.9 MET-hweek(-1)) were randomized to daily supplementation of 20g of COL (N=25) or an isoenergetic/isomacronutrient placebo (PLA) (N=28) for 12weeks. Venous blood was collected at baseline and at 12weeks and unstimulated saliva samples at 4 weeks intervals. There was a significantly lower proportion of URI days and number of URI episodes with COL compared to PLA over the 12weeks (p0.05), which does not support previously suggested mechanisms. In a subset of participants (COL=14, PLA=17), real-time quantitative PCR, targeting the 16S rRNA gene showed there was an increase in salivary bacterial load over the 12 weeks period with PLA (p

KW - URTI

KW - innate immunity

KW - mucosal immunity

KW - microbiome

KW - 16S rRNA

KW - metabolomics

UR - http://hdl.handle.net/2160/13129

U2 - 10.1016/j.bbi.2013.10.032

DO - 10.1016/j.bbi.2013.10.032

M3 - Article

C2 - 24200515

VL - 39