Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping

Type Article
Original languageEnglish
Pages (from-to)767-770
Number of pages4
JournalGenome
Volume61
Issue number10
Early online date05 Sep 2018
DOI
Publication statusE-pub ahead of print - 05 Sep 2018
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Abstract

Height is an important characteristic in the equine industry although little is known about its genetic control in native British breeds of ponies. This study aimed to map QTL data with the withers height in 4 pony breeds native to the British Isles, including 2 different sections within Welsh Cobs. In this study,
a genome-wide analysis approach using the Illumina EquineSNP50 Infinium BeadChip was applied to 105 ponies and cobs. Analysis identified 222 highly significant height-associated SNPs (P ≤10-5), among which three SNPs on ECA9 have also been previously reported elsewhere. The highest number of significant SNPs associated to height in the native British horses were located on ECA1, ECA8 and ECA16

Keywords

  • height, horse, single nucleotide polymorphisms, genome wide association, high density genotyping, quantitative trait loci