Classification of microcalcification clusters in digital mammograms using a stack generalization based classifier

Authors Organisations
Type Article
Original languageEnglish
Article number76
JournalJournal of Imaging
Issue number9
Early online date12 Sep 2019
Publication statusE-pub ahead of print - 12 Sep 2019
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This paper presents a machine learning based approach for the discrimination of malignant and benign microcalcification (MC) clusters in digital mammograms. A series of morphological operations were carried out to facilitate the feature extraction from segmented microcalcification. A combination ofmorphological, texture, and distribution features fromindividualMC components and MC clusters were extracted and a correlation-based feature selection technique was used. The clinical relevance of the selected features is discussed. The proposed method was evaluated using three different databases: OPTIMAM, DDSM, and MIAS. The best classification accuracy (95.00 +/- 0.57%) was achieved for OPTIMAM using a stack generalization classifier with 10-fold cross validation obtaining an Az value equal to 0.97 +/- 0.01.


  • digital mammogram, microcalcification, stack generalization, classification, morphological features