Department of Biological, Environmental and Rural Sciences
Edward Llwyd Building
PhD on understanding how parasitic flatworms metabolise anthelmintics. After a Medical Research Council postdoctoral post at Aberystwyth in parasite biochemistry gained experience in biotechnology at the Leicester BioCentre. In 1992 was awarded a Wellcome Trust Fellowship based at Nottingham University exploring parasite defences against immune assault. A Senior Research Fellowship at the Leicester Pharmacy School (1994-97) provided opportunities in target based drug design and lead compound synthesis. Established proteomics laboratories dedicated to parasite-host interactions during readership posts at the Universities of Aberystwyth and Liverpool. Returned to Aberystwyth as a Professor in Parasitology in 2007. Has held a number of research contracts to address key problems in parasite control (vaccine, drug and diagnostic discovery).
My current research interest is to resolve using functional genomics how liver and rumen fluke parasites interact with their respective host environments. To date, new parasite proteins have been discovered to support drug and vaccine development and diagnostics . I am also interested in developing new molecular tools to measure anthelmintic resistance in liver fluke and a protein biomarker panel has been identified to measure Triclabendazole (TCBZ) failure and resistance for new laboratory and penside tests.