Dr Manfred Beckmann PhD

Lecturer

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University website profile

Department of Biological, Environmental and Rural Sciences

Postal address
Aberystwyth University
Edward Llwyd Building
Penglais
Aberystwyth
United Kingdom of Great Britain and Northern Ireland
Contact
Phone: 01970 622340
ORCID: 0000-0002-4320-5001

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  1. 2022
  2. Published

    Defining Fatty Acid Changes Linked to Rumen Development, Weaning and Growth in Holstein-Friesian Heifers

    Taylor, E., Han, J., Fan, C., Beckmann, M., Hewinson, G., Rooke, D., Koets, A. & Mur, L., 20 Apr 2022, In: Metabolites. 12, 5, 14 p., 374.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/metabo12050374
  3. Published

    Metabolomic changes in Mycobacterium avium subsp. paratuberculosis (MAP) challenged Holstein–Friesian cattle highlight the role of serum amino acids as indicators of immune system activation

    Taylor, E., Beckmann, M., Markey, B. K., Gordon, S. V., Hewinson, G., Rooke, D. & Mur, L., 23 Mar 2022, In: Metabolomics. 18, 4, 12 p., 21.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s11306-022-01876-w
  4. 2021
  5. Published

    Metabolomic Changes in Naturally MAP-Infected Holstein–Friesian Heifers Indicate Immunologically Related Biochemical Reprogramming

    Taylor, E., Beckmann, M., Villarreal-Ramos, B., Vordermeier, M., Hewinson, G., Rooke, D., Mur, L. & Koets, A., 23 Oct 2021, In: Metabolites. 11, 11, 15 p., 727.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/metabo11110727
  6. Published

    Allotetraploidization in Brachypodium May Have Led to the Dominance of One Parent’s Metabolome in Germinating Seeds

    Skalska, A., Wolny, E., Beckmann, M., Doonan, J., Hasterok, R. & Mur, L., 07 Apr 2021, In: Cells. 10, 4, 16 p., e828.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/cells10040828
  7. Published

    Index measures for oak decline severity using phenotypic descriptors

    Finch, J., Brown, N., Beckmann, M., Denman, S. & Draper, J., 01 Apr 2021, In: Forest Ecology and Management. 485, 118948.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.foreco.2021.118948
  8. Published

    Dietary starch concentration influences milk protein via the phenylalanine and tyrosine metabolism in early lactation Holstein-Friesian dairy cows

    Taylor, E., McCaughern, J., Beckmann, M., Mackenzie, A., Mur, L. & Sinclair, L., Apr 2021, p. 97. 1 p.

    Research output: Contribution to conference › Abstract › peer-review

    DOI: 10.1016/j.anscip.2021.03.119
  9. Published

    Metabolomic changes in Mycobacterium avium subsp. paratuberculosis (MAP) inoculated Holstein-Friesian cattle suggest metabolites indicative of MAP exposure

    Taylor, E., Beckmann, M., Markey, B. K., Gordon, S. V., Hewinson, G., Rooke, D. & Mur, L., Apr 2021, p. 152. 1 p.

    Research output: Contribution to conference › Abstract › peer-review

    DOI: 10.1016/j.anscip.2021.03.183
  10. Published

    Metabolomic Variation Aligns with Two Geographically Distinct Subpopulations of Brachypodium Distachyon before and after Drought Stress

    Skalska, A., Beckmann, M., Corke, F., Savas Tuna, G., Tuna, M., Doonan, J., Hasterok, R. & Mur, L., 19 Mar 2021, In: Cells. 10, 3, 15 p., 683.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/cells10030683
  11. 2020
  12. Published

    Challenges Associated With the Design and Deployment of Food Intake Urine Biomarker Technology for Assessment of Habitual Diet in Free-Living Individuals and Populations: A Perspective

    Beckmann, M., Wilson, T., Lloyd, A., Torres, D. P. M., Goios, A. C. L., Willis, N. D., Lyons, L., Phillips, H., Mathers, J. M. & Draper, J., 25 Nov 2020, In: Frontiers in Nutrition. 7, 19 p., 602515.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3389/fnut.2020.602515
  13. Published

    Design and Characterisation of a Randomized Food Intervention That Mimics Exposure to a Typical UK Diet to Provide Urine Samples for Identification and Validation of Metabolite Biomarkers of Food Intake

    Willis, N. D., Lloyd, A., Xie, L., Stiegler, M., Tailliart, K., Garcia-Perez, I., Chambers, E., Beckmann, M., Draper, J. & Mathers, J. C., 21 Oct 2020, In: Frontiers in Nutrition. 7, 16 p., 561010.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3389/fnut.2020.561010
  14. E-pub ahead of print

    Calystegines are Potential Urine Biomarkers for Dietary Exposure to Potato Products

    Beckmann, M., Lloyd, A., Wilson, T., Torres, D. P. M., Goios, A. C. L., Willis, N. D., Lyons, L., Phillips, H., Mathers, J. C., Nash, R. J., Sharp, H. & Draper, J., 29 Sep 2020, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 64, 11 p., 2000515.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/mnfr.202000515
  15. E-pub ahead of print

    A Standardized Strategy for Simultaneous Quantification of Urine Metabolites to Validate Development of a Biomarker Panel Allowing Comprehensive Assessment of Dietary Exposure

    Beckmann, M., Wilson, T., Zubair, H., Lloyd, A., Lyons, L., Phillips, H., Tailliart, K., Gregory, N., Thatcher, R., Garcia-Perez, I., Frost, G., Mathers, J. M. & Draper, J., 28 Sep 2020, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 15 p., 2000517.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/mnfr.202000517
  16. Published

    Dietary metabotype modelling predicts individual responses to dietary interventions

    Garcia-Perez, I., Posma, J. M., Chambers, E., Mathers, J. C., Draper, J., Beckmann, M., Nicholson, J. K., Holmes, E. & Frost, G., 17 Jun 2020, In: Nature Food. 1, p. 355–364 10 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1038/s43016-020-0092-z
  17. Published

    Developing community-based urine sampling methods to deploy biomarker technology for assessment of dietary exposure

    Lloyd, A., Wilson, T., Willis, N. D., Lyons, L., Phillips, H., Janssen, H., Stiegler, M., Xie, L., Tailliart, K., Beckmann, M., Stevenson, L., Mathers, J. C. & Draper, J., 11 Jun 2020, In: Public Health Nutrition. 23, 17, p. 3081–3092

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1017/S136898002000097X
  18. Published

    No Influence of Low-, Medium-, or High-Dose Tyrosine on Exercise in a Warm Environment

    Tumilty, L., Gregory, N., Beckmann, M. & Thatcher, R., 01 Jun 2020, In: Medicine and Science in Sports and Exercise. 52, 6, p. 1404-1413 10 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1249/MSS.0000000000002245
  19. 2019
  20. Published

    Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measure of Dietary Exposure in Adults Using Metabolite Biomarkers

    Wilson, T., Garcia-Perez, I., Posma, J. M., Lloyd, A., Chambers, E. S., Tailliart, K., Zubair, H., Beckmann, M., Mathers, J. C., Holmes, E., Frost, G. & Draper, J., 26 Jun 2019, In: Journal of Nutrition. 149, 10, p. 1692-1700 9 p., nxz138.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1093/jn/nxz138
  21. Published

    The anti-mycobacterial activity of a diterpenoid-like molecule operates through nitrogen and amino acid starvation

    Crusco, A., Alves Baptista, R., Bhowmick, S., Beckmann, M., Mur, L., Westwell, A. D. & Hoffmann, K., 25 Jun 2019, In: Frontiers in Microbiology. 10, 01444.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3389/fmicb.2019.01444
  22. E-pub ahead of print

    Developing a food exposure and urine sampling strategy for dietary exposure biomarker validation in free-living individuals

    Lloyd, A., Willis, N. D., Wilson, T., Zubair, H., Xie, L., Chambers, E. S., Garcia-Perez, I., Tailliart, K., Beckmann, M., Mathers, J. C. & Draper, J., 03 Jun 2019, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 1900062.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/mnfr.201900062
  23. E-pub ahead of print

    Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation and Untargeted Metabolomics

    Crusco, A., Whiteland, H., Baptista, R., Forde-Thomas, J., Beckmann, M., Mur, L., Nash, R., Westwell, A. D. & Hoffmann, K., 28 May 2019, (E-pub ahead of print) In: ACS Infectious Diseases.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1021/acsinfecdis.9b00034
  24. Published

    Addressing the pitfalls when designing intervention studies to discover and validate biomarkers or habitual dietary intake

    Lloyd, A., Willis, N. D., Wilson, T., Zubair, H., Chambers, E., Garcia-Perez, I., Xie, L., Tailliart, K., Beckmann, M., Mathers, J. C. & Draper, J., 02 May 2019, In: Metabolomics. 15, 5, 12 p., 72.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s11306-019-1532-3
  25. Published

    Defining Metabolic Rewiring in Lung Squamous Cell Carcinoma

    Paes De Araujo, R., Bertoni, N., Seneda, A. L., Felix, T., Carvalho, M., Lewis, K. E., Hasimoto, É. N., Beckmann, M., Drigo, S. A., Reis, P. P. & Mur, L., 07 Mar 2019, In: Metabolites. 9, 3, 47.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3390/metabo9030047
  26. 2018
  27. Published

    Temporal metabolic partitioning of the yeast and protist cellular networks: the cell is a global scale-invariant (fractal or self-similar) multioscillator

    Lloyd, D., Murray, D. B., Aon, M. A., Cortassa, S., Roussel, M. R., Beckmann, M. & Poole, R. K., 04 Dec 2018, In: Journal of Biomedical Optics. 24, 5, 051404.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1117/1.JBO.24.5.051404
  28. Published

    Plant species and heavy metals affect biodiversity of microbial communities associated with metal-tolerant plants in metalliferous soils

    Borymski, S., Cycoń, M., Beckmann, M., Mur, L. & Piotrowska-Seget, Z., 16 Jul 2018, In: Frontiers in Microbiology. 9, 01425.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3389/fmicb.2018.01425
  29. E-pub ahead of print

    Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824)

    Baptista, R., Fazakerley, D. M., Beckmann, M., Baillie, L. & Mur, L., 23 Mar 2018, (E-pub ahead of print) In: Scientific Reports. 8, 1, 7 p., 5084.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1038/s41598-018-23110-1
  30. 2017
  31. Published

    Anti-inflammatory properties of an extract of M. ilicifolia in the human intestinal epithelial Caco-2 cell line

    Wonfor, R., Natoli, M., Shah, I., Beckmann, M., Nash, R. & Nash, D., 14 Sep 2017, In: Journal of Ethnopharmacology. 209, p. 283-287 5 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.jep.2017.08.006
  32. Published

    Objective assessment of dietary patterns by use of metabolic phenotyping: A randomised, controlled, crossover trial

    Garcia-Perez, I., Posma, J. M., Gibson, R., Chambers, E. S., Hanson, T. H., Vestergaard, H., Hansen, T., Beckmann, M., Pedersen, O., Elliott, P., Stamler, J., Nicholson, J. K., Draper, J., Mathers, J. C., Holmes, E. & Frost, G., 31 Mar 2017, In: Lancet Diabetes and Endocrinology. 5, 3, p. 184-195 12 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/S2213-8587(16)30419-3
  33. Published

    Diversity and association of phenotypic and metabolomic traits in the close model grasses Brachypodium distachyon, B. stacei and B. hybridum

    López-Álvarez, D., Zubair, H., Beckmann, M., Draper, J. & Catalán, P., 01 Mar 2017, In: Annals of Botany. 119, 4, p. 545-561

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1093/aob/mcw239
  34. Published

    Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry plasma lipidomics can distinguish between canine breeds despite uncontrolled environmental variability and non-standardized diets: Plasma lipidome of dog breeds using UHPLC-HRM

    Lloyd, A., Beckmann, M., Wilson, T., Tailliart, K., Allaway, D. & Draper, J., 01 Feb 2017, In: Metabolomics. 13, 15.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s11306-016-1152-0
  35. Published

    Vitamin D status modulates innate immune responses and metabolic profiles following acute prolonged cycling

    Jones, A. W., Mironas, A., Mur, L., Beckmann, M., Thatcher, R. & Davison, G., 2017.

    Research output: Contribution to conference › Abstract › peer-review

  36. 2016
  37. Published

    Developing community-based urine sampling methods to facilitate dietary exposure biomarker technology for population assessment

    Wilson, T., Willis, N. D., Zubair, H., Beckmann, M., Xie, L., Tailliart, K., Lloyd, A., Mathers, J. C. & Draper, J., 24 Nov 2016, In: Proceedings of the Nutrition Society. 75, OCE3, E240.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1017/S002966511600255X
  38. Published

    Quantification of dietary biomarkers in spot urine samples reflects the intake of foods of UK high public health importance

    Lloyd, A., Zubair, H., Willis, N. D., Wilson, T., Xie, L., Tailliart, K., Chambers, E. S., Garcia-Perez, I., Holmes, E., Frost, G., Mathers, J. C., Beckmann, M. & Draper, J., 24 Nov 2016, In: Proceedings of the Nutrition Society. 75, OCE3, E248.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1017/S0029665116002639
  39. Published

    The metabolomic detection of lung cancer biomarkers in sputum

    Cameron, S., Lewis, K. E., Beckmann, M., Allison, G., Ghosal, R., Lewis, P. D. & Mur, L., 30 Apr 2016, In: Lung Cancer. 94, N/A, p. 88-95 8 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.lungcan.2016.02.006
  40. Published

    Characterisation of the main drivers of intra- and inter- breed variability in the plasma metabolome of dogs

    Lloyd, A., Beckmann, M., Tailliart, K., Brown, W. Y., Draper, J. & Allaway, D., 01 Apr 2016, In: Metabolomics. 12, 4, 72.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s11306-016-0997-6
  41. Published

    An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake

    Garcia-Perez, I., Posma, J. M., Chambers, E. S., Nicholson, J. K., Mathers, J. C., Beckmann, M., Draper, J., Holmes, E. & Frost, G., 23 Mar 2016, In: Journal of Agricultural and Food Chemistry. 64, 11, p. 2423-2431 9 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1021/acs.jafc.5b05878
  42. Published

    Changes in the human plasma and urinary metabolome associated with acute dietary exposure to sucrose and the identification of potential biomarkers of sucrose intake

    Beckmann, M., Joosen, A. M., Clarke, M. M., Mugridge, O., Frost, G., Engel, B., Tailliart, K., Lloyd, A., Draper, J. & Lodge, J. K., 01 Feb 2016, In: Molecular Nutrition and Food Research. 60, 2, p. 444-457

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/mnfr.201500495
  43. 2015
  44. Published

    Dietary compliance in a human intervention study investigating the impact of specific foods on urinary metabolites

    Willis, N. D., Dodds, S. E., Lloyd, A., Xie, L., Chambers, E. S., Garcia-Perez, I., Frost, G., Beckmann, M., Draper, J. & Mathers, J. C., 15 Apr 2015, In: Proceedings of the Nutrition Society. 74, OCE1, 1 p., E127.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1017/S0029665115001421
  45. Published

    No effect of oral tyrosine administration on mood and motivation or heart rate variability during endurance performance in the heat

    Tumilty, L., Thatcher, R., Beckmann, M. & Davison, G., 2015.

    Research output: Contribution to conference › Poster

  46. 2014
  47. Published

    Failure of oral tyrosine supplementation to improve exercise performance in the heat

    Tumilty, L., Davison, G., Beckmann, M. & Thatcher, R., Jul 2014, In: Medicine and Science in Sports and Exercise. 46, 7, p. 1417-25 9 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1249/MSS.0000000000000243
  48. Published

    Acute oral tyrosine supplementation does not prevent the decline in maximal handgrip force in hyperthermic subjects

    Tumilty, L., Thatcher, R., Beckmann, M. & Davison, G., 2014.

    Research output: Contribution to conference › Poster

  49. 2013
  50. Published

    Hydroxylated phenylacetamides derived from bioactive benzoxazinoids are bioavailable in humans after habitual consumption of whole grain sourdough rye bread

    Beckmann, M., Lloyd, A., Halder, S., Seal, C., Brandt, K. & Draper, J., Oct 2013, In: Molecular Nutrition and Food Research. 57, 10, p. 1859-1873 15 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/mnfr.201200777
  51. Published

    Dietary exposure biomarker-lead discovery based on Metabolomics analysis of urine samples

    Beckmann, M., Lloyd, A., Halder, S., Fave, G., Seal, C., Brandt, K., Mathers, J. C. & Draper, J., Aug 2013, In: Proceedings of the Nutrition Society. 72, 3, p. 352-361 10 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1017/S0029665113001237
  52. Published

    Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat

    Tumilty, L., Davison, G., Beckmann, M. & Thatcher, R., Jun 2013, In: European Journal of Applied Physiology. 113, 6, p. 1511-1522 12 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s00421-012-2577-4
  53. Published

    Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: A Review

    Draper, J., Lloyd, A., Goodacre, R. & Beckmann, M., Mar 2013, In: Metabolomics. 9, 1 Supplement, p. S4–S29 26 p.

    Research output: Contribution to journal › Literature review › peer-review

    DOI: 10.1007/s11306-012-0449-x
  54. Published

    Data-driven strategy for the discovery of potential urinary biomarkers of habitual dietary exposure

    Lloyd, A., Beckmann, M., Haldar, S., Seal, C., Brandt , K. & Draper, J., 01 Feb 2013, In: American Journal of Clinical Nutrition. 97 , 2 , p. 377-389 12 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.3945/ajcn.112.048033
  55. 2012
  56. Published

    Deciphering systemic wound responses of the pumpkin extrafascicular phloem by metabolomics and stable isotope-coded protein labeling (ICPL).

    Graupels, F., Sarioglu, H., Beckmann, M., Hause, B., Spannagl, M., Draper, J., Lindermayr, C. & Durner, J., Dec 2012, In: Plant Physiology. 160, 4, p. 2285-99 15 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.​1104/​pp.​112.​205336
  57. Published

    Detection and quantification of tissue of origin in salmon and veal products using methylation sensitive AFLPs

    Rodriguez Lopez, C. M., Morán, P., Lago, F., Espiñeira, M., Beckmann, M. & Olmo, S. C. D., 15 Apr 2012, In: Food Chemistry. 131, 4, p. 1493-1498 6 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.foodchem.2011.09.120
  58. Published

    Acute oral tyrosine administration does not improve exercise performance in the heat in man

    Tumilty, L., Davison, G., Beckmann, M. & Thatcher, R., 2012, p. 93.

    Research output: Contribution to conference › Poster

  59. Published

    Effects of changing rumen protozoa populations in sheep on plasma metabolomic profiles

    Belanche Gracia, A., Beckmann, M., Moorby, J., De La Fuente Oliver, G. & Newbold, C. J., 2012.

    Research output: Contribution to conference › Other

  60. Published

    Fourier transform ion cyclotron resonance mass spectrometry for plant metabolite profiling and metabolite identification

    Allwood, J. W., Parker, D., Beckmann, M., Draper, J. & Goodacre, R., 2012, Methods in Molecular Biology. Springer Nature, p. 157-176 20 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    DOI: 10.1007/978-1-61779-594-7_11
  61. 2011
  62. Published

    Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples

    Favé, G., Beckmann, M., Lloyd, A., Zhou, S., Harold, G., Lin, W., Tailliart, K., Xie, L., Draper, J. & Mathers, J. C., 01 Dec 2011, In: Metabolomics. 7, 4, p. 469-484 16 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1007/s11306-011-0289-0
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Urine Medicine & Life Sciences
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Metabolite Chemical Compounds
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Biomarkers Medicine & Life Sciences
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Mass Spectrometry Medicine & Life Sciences
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Food Medicine & Life Sciences
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