Prof Karl Hoffmann PhD

Professor

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University website profile

Department of Biological, Environmental and Rural Sciences

Postal address
Aberystwyth University
Edward Llwyd Building
Penglais
Aberystwyth
United Kingdom of Great Britain and Northern Ireland
Contact
Phone: 01970 622237
Link(s)
ORCID: 0000-0002-3932-5502

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  1. 2020
  2. Published

    DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells

    Kuipers, M. E., Nolte-‘t Hoen, E. N. M., van der Ham, A. J., Ozir-Fazalalikhan, A., Nguyen, D. L., de Korne, C. M., Koning, R. I., Tomes, J., Hoffmann, K., Smits, H. H. & Hokke, C. H., 20 Apr 2020, In : Journal of Extracellular Vesicles. 9, 1, 19 p., 1753420.

    Research output: Contribution to journal › Article

    DOI: 10.1080/20013078.2020.1753420
  3. 2019
  4. Published

    The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets

    Whatley, K., Padalino, G., Whiteland, H., Geyer, K. K., Hulme, B. J., Chalmers, I., Forde-Thomas, J., Ferla, S., Brancale, A. & Hoffmann, K., 15 Nov 2019, In : PLoS Neglected Tropical Diseases. 13, 11, e0007693.

    Research output: Contribution to journal › Article

    DOI: 10.1371/journal.pntd.0007693
  5. Published

    Erratum to ‘Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni’ [IJP Drugs Drug Resist. 8 (2018) 559–570]

    Padalino, G., Ferla, S., Brancale, A., Chalmers, I. & Hoffmann, K., 02 Jul 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 91 1 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijpddr.2019.07.001
  6. Published

    Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity

    Farias, L. P., Chalmers, I., Perally, S., Rofatto, H. K., Jackson, C. J., Brown, M., Khouri, M. I., Barbosa, M. M. F., Hensbergen, P. J., Hokke, C. H., Leite, L. C. C. & Hoffmann, K., 01 Jul 2019, In : International Journal for Parasitology. 49, 8, p. 593-599 7 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijpara.2019.03.003
  7. Published

    The anti-mycobacterial activity of a diterpenoid-like molecule operates through nitrogen and amino acid starvation

    Crusco, A., Alves Baptista, R., Bhowmick, S., Beckmann, M., Mur, L., Westwell, A. D. & Hoffmann, K., 25 Jun 2019, In : Frontiers in Microbiology. 10, 01444.

    Research output: Contribution to journal › Article

    DOI: 10.3389/fmicb.2019.01444
  8. E-pub ahead of print

    Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation and Untargeted Metabolomics

    Crusco, A., Whiteland, H., Baptista, R., Forde-Thomas, J., Beckmann, M., Mur, L., Nash, R., Westwell, A. D. & Hoffmann, K., 28 May 2019, In : ACS Infectious Diseases.

    Research output: Contribution to journal › Article

    DOI: 10.1021/acsinfecdis.9b00034
  9. Published

    Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

    Wannaporn, I., Mann, V., Karinshak, S., Coghlan, A., Rinaldi, G., Sankaranarayanan, G., Chaidee, A., Tanno, T., Kumkhaek, C., Prangtaworn, P., Mentink-Kane, M. M., Cochran, C. J., Driguez, P., Holroyd, N., Tracey, A., Rodpai, R., Everts, B., Hokke, C. H., Hoffmann, K., Berriman, M. & 1 others, Brindley, P. J., 15 Jan 2019, In : eLife. 8, e41337.

    Research output: Contribution to journal › Article

    DOI: 10.7554/eLife.41337
  10. 2018
  11. Published

    An Abeis procera - Derived tetracyclic triterpene containing a steroid-like core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni

    Whiteland, H., Chakroborty, A., Forde-Thomas, J., Crusco, A., Cookson, A., Hollinshead, J., Fenn, C., Bartholomew, B., Holdsworth, P. A., Fisher, M., Nash, R. & Hoffmann, K., 01 Dec 2018, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, p. 465-474 10 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijpddr.2018.10.009
  12. Published

    Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

    Padalino, G., Ferla, S., Brancale, A., Chalmers, I. & Hoffmann, K., 01 Dec 2018, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, p. 559-570 12 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijpddr.2018.10.005
  13. Published

    Corrigendum to ‘the anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities’: [Int. J. Parasitol. Drugs and Drug Resist. 8 (2018) 213–222]

    Geyer, K. K., Munshi, S. E., Vickers, M., Squance, M., Wilkinson, T., Berrar, D., Chaparro, C., Swain, M. & Hoffmann, K., 01 Dec 2018, In : International Journal for Parasitology: Drugs and Drug Resistance. 8, 3, p. 493 1 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijpddr.2018.07.002
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