Prof John Draper B.Sc. and Ph.D.
Chair
- ChairDepartment of Life Sciences - Teaching And Research
Department of Life Sciences
Edward Llwyd Building
Penglais
Aberystwyth
- 2022
Spectral binning as an approach to post-acquisition processing of high resolution FIE-MS metabolome fingerprinting data
Finch, J., Wilson, T., Lyons, L., Phillips, H., Beckmann, M. & Draper, J., 02 Aug 2022, In: Metabolomics. 18, 8, 9 p., 64.Research output: Contribution to journal › Article › peer-review
Assessing Adherence to Healthy Dietary Habits Through the Urinary Food Metabolome: Results From a European Two-Center Study
Castellano-Escuder, P., González-Domínguez, R., Vaillant, M. F., Casas-Agustench, P., Hidalgo-Liberona, N., Estanyol-Torres, N., Wilson, T., Beckmann, M., Lloyd, A., Oberli, M., Moinard, C., Pison, C., Borel, J. C., Joyeux-Faure, M., Sicard, M., Artemova, S., Terrisse, H., Dancer, P., Draper, J., Sánchez-Pla, A., & 1 othersAndres-Lacueva, C., 09 Jun 2022, In: Frontiers in Nutrition. 9, 11 p., 880770.Research output: Contribution to journal › Article › peer-review
- 2021
Nutrition and frailty: Opportunities for prevention and treatment
Ni Lochlainn, M., Cox, N. J., Wilson, T., Hayhoe, R. P. G., Ramsay, S. E., Granic, A., Isanejad, M., Roberts, H. C., Wilson, D., Welch, C., Hurst, C., Atkins, J. L., Mendonça, N., Horner, K., Tuttiett, E. R., Morgan, Y., Heslop, P., Williams, E. A., Steves, C. J., Greig, C., & 6 othersDraper, J., Corish, C. A., Welch, A., Witham, M. D., Sayer, A. A. & Robinson, S., 09 Jul 2021, In: Nutrients. 13, 7, 20 p., 2349.Research output: Contribution to journal › Review article › peer-review
DOI: 10.3390/nu13072349UK Nutrition Research Partnership (NRP) workshop: Forum on advancing dietary intake assessment
de la Hunty, A., Buttriss, J., Draper, J., Roche, H., Levey, G., Florescu, A., Penfold, N. & Frost, G., 04 Jun 2021, In: Nutrition Bulletin. 46, 2, p. 228-237 10 p.Research output: Contribution to journal › Editorial
DOI: 10.1111/nbu.12501Index measures for oak decline severity using phenotypic descriptors
Finch, J., Brown, N., Beckmann, M., Denman, S. & Draper, J., 01 Apr 2021, In: Forest Ecology and Management. 485, 118948.Research output: Contribution to journal › Article › peer-review
- Published
Application of Metabolomics for the Assessment of Process-induced Changes in Whole Grain Foods
Lloyd, A., Tailliart, K., Beckmann, M. & Draper, J., 01 Jan 2021, Whole Grains and Health: Second Edition. Landberg, R. (ed.). Wiley, p. 351-374 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- 2020
Challenges Associated With the Design and Deployment of Food Intake Urine Biomarker Technology for Assessment of Habitual Diet in Free-Living Individuals and Populations: A Perspective
Beckmann, M., Wilson, T., Lloyd, A., Torres, D. P. M., Goios, A. C. L., Willis, N. D., Lyons, L., Phillips, H., Mathers, J. M. & Draper, J., 25 Nov 2020, In: Frontiers in Nutrition. 7, 19 p., 602515.Research output: Contribution to journal › Article › peer-review
Design and Characterisation of a Randomized Food Intervention That Mimics Exposure to a Typical UK Diet to Provide Urine Samples for Identification and Validation of Metabolite Biomarkers of Food Intake
Willis, N. D., Lloyd, A., Xie, L., Stiegler, M., Tailliart, K., Garcia-Perez, I., Chambers, E., Beckmann, M., Draper, J. & Mathers, J. C., 21 Oct 2020, In: Frontiers in Nutrition. 7, 16 p., 561010.Research output: Contribution to journal › Article › peer-review
Calystegines are Potential Urine Biomarkers for Dietary Exposure to Potato Products
Beckmann, M., Lloyd, A., Wilson, T., Torres, D. P. M., Goios, A. C. L., Willis, N. D., Lyons, L., Phillips, H., Mathers, J. C., Nash, R. J., Sharp, H. & Draper, J., 29 Sep 2020, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 64, 11 p., 2000515.Research output: Contribution to journal › Article › peer-review
A Standardized Strategy for Simultaneous Quantification of Urine Metabolites to Validate Development of a Biomarker Panel Allowing Comprehensive Assessment of Dietary Exposure
Beckmann, M., Wilson, T., Zubair, H., Lloyd, A., Lyons, L., Phillips, H., Tailliart, K., Gregory, N., Thatcher, R., Garcia-Perez, I., Frost, G., Mathers, J. M. & Draper, J., 28 Sep 2020, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 15 p., 2000517.Research output: Contribution to journal › Article › peer-review
Dietary metabotype modelling predicts individual responses to dietary interventions
Garcia-Perez, I., Posma, J. M., Chambers, E., Mathers, J. C., Draper, J., Beckmann, M., Nicholson, J. K., Holmes, E. & Frost, G., 17 Jun 2020, In: Nature Food. 1, p. 355–364 10 p.Research output: Contribution to journal › Article › peer-review
Developing community-based urine sampling methods to deploy biomarker technology for assessment of dietary exposure
Lloyd, A., Wilson, T., Willis, N. D., Lyons, L., Phillips, H., Janssen, H., Stiegler, M., Xie, L., Tailliart, K., Beckmann, M., Stevenson, L., Mathers, J. C. & Draper, J., 11 Jun 2020, In: Public Health Nutrition. 23, 17, p. 3081–3092Research output: Contribution to journal › Article › peer-review
- 2019
Perspective: Dietary Biomarkers of Intake and Exposure - Exploration with Omics Approaches
Maruvada, P., Lampe, J. W., Wishart, D. S., Barupal, D., Chester, D. N., Dodd, D., Djoumbou-Feunang, Y., Dorrestein, P. C., Dragsted, L. O., Draper, J., Duffy, L. C., Dwyer, J. T., Emenaker, N. J., Fiehn, O., Gerszten, R. E., Hu, F. B., Karp, R. W., Klurfeld, D. M., Laughlin, M. R., Little, A. R., & 16 othersLynch, C. J., Moore, S. C., Nicastro, H. L., O'Brien, D. M., Ordovás, J. M., Osganian, S. K., Playdon, M., Prentice, R., Raftery, D., Reisdorph, N., Roche, H. M., Ross, S. A., Sang, S., Scalbert, A., Srinivas, P. R. & Zeisel, S. H., 06 Aug 2019, In: Advances in Nutrition. nmz075.Research output: Contribution to journal › Article › peer-review
Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measure of Dietary Exposure in Adults Using Metabolite Biomarkers
Wilson, T., Garcia-Perez, I., Posma, J. M., Lloyd, A., Chambers, E. S., Tailliart, K., Zubair, H., Beckmann, M., Mathers, J. C., Holmes, E., Frost, G. & Draper, J., 26 Jun 2019, In: Journal of Nutrition. 149, 10, p. 1692-1700 9 p., nxz138.Research output: Contribution to journal › Article › peer-review
DOI: 10.1093/jn/nxz138Developing a food exposure and urine sampling strategy for dietary exposure biomarker validation in free-living individuals
Lloyd, A., Willis, N. D., Wilson, T., Zubair, H., Xie, L., Chambers, E. S., Garcia-Perez, I., Tailliart, K., Beckmann, M., Mathers, J. C. & Draper, J., 03 Jun 2019, (E-pub ahead of print) In: Molecular Nutrition and Food Research. 1900062.Research output: Contribution to journal › Article › peer-review
Addressing the pitfalls when designing intervention studies to discover and validate biomarkers or habitual dietary intake
Lloyd, A., Willis, N. D., Wilson, T., Zubair, H., Chambers, E., Garcia-Perez, I., Xie, L., Tailliart, K., Beckmann, M., Mathers, J. C. & Draper, J., 02 May 2019, In: Metabolomics. 15, 5, 12 p., 72.Research output: Contribution to journal › Article › peer-review
- 2017
Use of biomarkers to assess fruit and vegetables intake
Woodside, J. V., Draper, J., Lloyd, A. & McKinley, M. C., 01 Aug 2017, In: Proceedings of the Nutrition Society. 76, 3, p. 308-315 8 p.Research output: Contribution to journal › Article › peer-review
Objective assessment of dietary patterns by use of metabolic phenotyping: A randomised, controlled, crossover trial
Garcia-Perez, I., Posma, J. M., Gibson, R., Chambers, E. S., Hanson, T. H., Vestergaard, H., Hansen, T., Beckmann, M., Pedersen, O., Elliott, P., Stamler, J., Nicholson, J. K., Draper, J., Mathers, J. C., Holmes, E. & Frost, G., 31 Mar 2017, In: Lancet Diabetes and Endocrinology. 5, 3, p. 184-195 12 p.Research output: Contribution to journal › Article › peer-review
Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers
Posma, J. M., Garcia-Perez, I., Heaton, J. C., Burdisso, P., Mathers, J. C., Draper, J., Lewis, M., Lindon, J. C., Frost, G., Holmes, E. & Nicholson, J. K., 21 Mar 2017, In: Analytical Chemistry. 89, 6, p. 3300-3309 10 p.Research output: Contribution to journal › Article › peer-review
Diversity and association of phenotypic and metabolomic traits in the close model grasses Brachypodium distachyon, B. stacei and B. hybridum
López-Álvarez, D., Zubair, H., Beckmann, M., Draper, J. & Catalán, P., 01 Mar 2017, In: Annals of Botany. 119, 4, p. 545-561Research output: Contribution to journal › Article › peer-review
DOI: 10.1093/aob/mcw239Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry plasma lipidomics can distinguish between canine breeds despite uncontrolled environmental variability and non-standardized diets: Plasma lipidome of dog breeds using UHPLC-HRM
Lloyd, A., Beckmann, M., Wilson, T., Tailliart, K., Allaway, D. & Draper, J., 01 Feb 2017, In: Metabolomics. 13, 15.Research output: Contribution to journal › Article › peer-review
- 2016
- Published
Developing community-based urine sampling methods to facilitate dietary exposure biomarker technology for population assessment
Wilson, T., Willis, N. D., Zubair, H., Beckmann, M., Xie, L., Tailliart, K., Lloyd, A., Mathers, J. C. & Draper, J., 24 Nov 2016, In: Proceedings of the Nutrition Society. 75, OCE3, E240.Research output: Contribution to journal › Article › peer-review
- Published
Quantification of dietary biomarkers in spot urine samples reflects the intake of foods of UK high public health importance
Lloyd, A., Zubair, H., Willis, N. D., Wilson, T., Xie, L., Tailliart, K., Chambers, E. S., Garcia-Perez, I., Holmes, E., Frost, G., Mathers, J. C., Beckmann, M. & Draper, J., 24 Nov 2016, In: Proceedings of the Nutrition Society. 75, OCE3, E248.Research output: Contribution to journal › Article › peer-review
Characterisation of the main drivers of intra- and inter- breed variability in the plasma metabolome of dogs
Lloyd, A., Beckmann, M., Tailliart, K., Brown, W. Y., Draper, J. & Allaway, D., 01 Apr 2016, In: Metabolomics. 12, 4, 72.Research output: Contribution to journal › Article › peer-review
An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake
Garcia-Perez, I., Posma, J. M., Chambers, E. S., Nicholson, J. K., Mathers, J. C., Beckmann, M., Draper, J., Holmes, E. & Frost, G., 23 Mar 2016, In: Journal of Agricultural and Food Chemistry. 64, 11, p. 2423-2431 9 p.Research output: Contribution to journal › Article › peer-review
Changes in the human plasma and urinary metabolome associated with acute dietary exposure to sucrose and the identification of potential biomarkers of sucrose intake
Beckmann, M., Joosen, A. M., Clarke, M. M., Mugridge, O., Frost, G., Engel, B., Tailliart, K., Lloyd, A., Draper, J. & Lodge, J. K., 01 Feb 2016, In: Molecular Nutrition and Food Research. 60, 2, p. 444-457Research output: Contribution to journal › Article › peer-review
- Published
Improving Efficiency and Reducing Waste in the Beef Supply Chain
Scollan, N., MacKintosh, S., Richardson, R. I., Singh, A., Mishra, N. & Draper, J., 2016, p. 211.Research output: Contribution to conference › Paper › peer-review
- Published
Variation in the M. longissumus texture and cooking loss from cattle within a commercial supply chain.
MacKintosh, S., Draper, J., Scott, A., Leemans, D., Morgan, S., Powell, H., Richardson, R. I. & Scollan, N., 2016, p. 138.Research output: Contribution to conference › Poster › peer-review
- 2015
- Published
Dietary compliance in a human intervention study investigating the impact of specific foods on urinary metabolites
Willis, N. D., Dodds, S. E., Lloyd, A., Xie, L., Chambers, E. S., Garcia-Perez, I., Frost, G., Beckmann, M., Draper, J. & Mathers, J. C., 15 Apr 2015, In: Proceedings of the Nutrition Society. 74, OCE1, 1 p., E127.Research output: Contribution to journal › Article › peer-review
- 2014
The food metabolome: A window over dietary exposure
Scalbert, A., Brennan, L., Manach, C., Andres-Lacueva, C., Dragsted, L. O., Draper, J., Rappaport, S. M., Van Der Hooft, J. J. J. & Wishart, D. S., 01 Jun 2014, In: American Journal of Clinical Nutrition. 99, 6, p. 1286-1308 23 p.Research output: Contribution to journal › Article › peer-review
Erratum to: Brachypodium distachyon: making hay with a wild grass: [Trends in Plant Science 13 (2008) 172–177]
Opanowicz, M., Vain, P., Draper, J., Parker, D. & Doonan, J., 01 Mar 2014, In: Trends in Plant Science. 19, 3, p. 193Research output: Contribution to journal › Correction › peer-review
- 2013
Merits of random forests emerge in evaluation of chemometric classifiers by external validation
Scott, I., Lin, W., Liakata, M., Wood, J. E., Vermeer, C. P., Allaway, D., Ward, J. L., Draper, J., Beale, M. H., Corol, D. I., Baker, J. M. & King, R. D., 01 Nov 2013, In: Analytica Chimica Acta. 801, p. 22-33 12 p., ACA232839.Research output: Contribution to journal › Article › peer-review
- Published
Hydroxylated phenylacetamides derived from bioactive benzoxazinoids are bioavailable in humans after habitual consumption of whole grain sourdough rye bread
Beckmann, M., Lloyd, A., Halder, S., Seal, C., Brandt, K. & Draper, J., Oct 2013, In: Molecular Nutrition and Food Research. 57, 10, p. 1859-1873 15 p.Research output: Contribution to journal › Article › peer-review
Dietary exposure biomarker-lead discovery based on Metabolomics analysis of urine samples
Beckmann, M., Lloyd, A., Halder, S., Fave, G., Seal, C., Brandt, K., Mathers, J. C. & Draper, J., Aug 2013, In: Proceedings of the Nutrition Society. 72, 3, p. 352-361 10 p.Research output: Contribution to journal › Article › peer-review
- Published
Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: A Review
Draper, J., Lloyd, A., Goodacre, R. & Beckmann, M., Mar 2013, In: Metabolomics. 9, 1 Supplement, p. S4–S29 26 p.Research output: Contribution to journal › Literature review › peer-review
Data-driven strategy for the discovery of potential urinary biomarkers of habitual dietary exposure
Lloyd, A., Beckmann, M., Haldar, S., Seal, C., Brandt , K. & Draper, J., 01 Feb 2013, In: American Journal of Clinical Nutrition. 97 , 2 , p. 377-389 13 p.Research output: Contribution to journal › Article › peer-review
- 2012
- Published
Deciphering systemic wound responses of the pumpkin extrafascicular phloem by metabolomics and stable isotope-coded protein labeling (ICPL).
Graupels, F., Sarioglu, H., Beckmann, M., Hause, B., Spannagl, M., Draper, J., Lindermayr, C. & Durner, J., Dec 2012, In: Plant Physiology. 160, 4, p. 2285-99 15 p.Research output: Contribution to journal › Article › peer-review
- Published
EPPN: High throughput plant phenotyping facilities at Aberystwyth
Doonan, J., Howarth, C., Camargo-Rodriguez, A., Allison, G., Swain, G., Gay, A. & Draper, J., 2012.Research output: Contribution to conference › Abstract
- Published
Fourier transform ion cyclotron resonance mass spectrometry for plant metabolite profiling and metabolite identification
Allwood, J. W., Parker, D., Beckmann, M., Draper, J. & Goodacre, R., 2012, Methods in Molecular Biology. Springer Nature, p. 157-176 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- 2011
- Published
Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples
Favé, G., Beckmann, M., Lloyd, A., Zhou, S., Harold, G., Lin, W., Tailliart, K., Xie, L., Draper, J. & Mathers, J. C., 01 Dec 2011, In: Metabolomics. 7, 4, p. 469-484 16 p.Research output: Contribution to journal › Article › peer-review
- Published
Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption
Lloyd, A., Beckmann, M., Favé, G., Mathers, J. C. & Draper, J., 01 Sep 2011, In: British Journal of Nutrition. 106, 6, p. 812-824 13 p.Research output: Contribution to journal › Article › peer-review
- Published
Use of mass spectrometry fingerprinting to identify urinary metabolites after consumption of specific foods
Lloyd, A., Favé, G., Beckmann, M., Lin, W., Tailliart, K., Xie, L., Mathers, J. C. & Draper, J., 24 Aug 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 981-991 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Metabolite analysis and metabolomics in the study of biotrophic interactions between plants and microbes
Draper, J., Rasmussen, S. & Zubair, H., 17 Mar 2011, Annual Plant Reviews. Hall, R. D. (ed.). Wiley, p. 25-59 35 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
- Published
Workshop Report Metabolomics and human nutrition
Primrose, S., Draper, J., Elsom, R., Kirkpatrick, V., Mathers, J. C., Seal, C., Beckmann, M., Haldar, S., Beattie, J. H., Lodge, J. K., Jenab, M., Keun, H. & Scalbert, A., 21 Jan 2011, In: British Journal of Nutrition. 105, 8, p. 1277-1283 7 p.Research output: Contribution to journal › Article › peer-review
- Published
Development of high throughput plant phenotyping facilities at Aberystwyth
Howarth, C., Gay, A., Draper, J. & Powell, W., 16 Jan 2011, Phenomics Workshop.Research output: Chapter in Book/Report/Conference proceeding › Conference Proceeding (Non-Journal item)
- Published
Choosing the number of labels in image segmentation
Liu, Y., Draper, J., Gay, A., Howarth, C. & Martin, R. R., 2011.Research output: Contribution to conference › Paper
- 2010
Enhancement of plant metabolite fingerprinting by machine learning
Scott, I., Vermeer, C. P., Liakata, M., Corol, D. I., Ward, J. L., Lin, W., Johnson, H. E., Whitehead, L., Kular, B., Baker, J. M., Walsh, S., Dave, A., Larson, T. R., Graham, I. A., Wang, T. L., King, R. D., Draper, J. & Beale, M. H., Aug 2010, In: Plant Physiology. 153, 4, p. 1506-1520 15 p.Research output: Contribution to journal › Article › peer-review
- Published
The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato.
Ward, J. L., Forcat, S., Beckmann, M., Bennett, M., Miller, S. J., Baker, J. M., Hawkins, N. D., Vermeer, C. P., Lu, C., Lin, W., Truman, W. M., Beale, M. H., Draper, J., Mansfield, J. W. & Grant, M., Aug 2010, In: Plant Journal. 63, 3, p. 443-457 15 p.Research output: Contribution to journal › Article › peer-review
- Published
Metabolite fingerprinting of urine suggests breed-specific dietary metabolism differences in domestic dogs
Beckmann, M., Enot, D. P. L., Overy, D. P., Scott, I., Jones, P. G., Allaway, D. & Draper, J., Apr 2010, In: British Journal of Nutrition. 103, 8, p. 1127-1138 12 p.Research output: Contribution to journal › Article › peer-review
- 2009
- Published
Metabolomic analysis reveals a common pattern of metabolic re-programming during invasion of three host plant species by Magnaporthe grisea
Parker, D. A., Beckmann, M., Zubair, H., Enot, D. P. L., Caracuel-Rios, Z., Overy, D. P., Snowdon, S., Talbot, N. J. & Draper, J., Sep 2009, In: Plant Journal. 59, 5, p. 723-737 15 p.Research output: Contribution to journal › Article › peer-review